OFF!® Botanicals® Insect Repellent IV repels mosquitoes black flies gnats and no-see-ums. OFF!® Botanicals® Insect Repellent Spritz repels mosquitoes that may carry West Nile virus when used as directed. Apply insect repellent directly onto skin or onto hands and then to skin for sensitive areas.OFF!® Botanicals® Insect Repellent Spritz is for pre-walk pre-picnic pre-hike pre-night out pre-every day! It s made with a plant-based active ingredient synthetically derived from pine oil extract.